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Bile Salts

Bile Salts

Bile salts are essential components of bile that facilitate the digestion and absorption of fats and fat-soluble vitamins in the small intestine. They are derived from cholesterol and play a crucial role in emulsifying dietary fats, making them easier to digest.

Indications

-Treatment of bile acid malabsorption -Support for liver function in conditions such as cholestasis -Management of certain types of liver disease -Aid in digestion and absorption of dietary fats in individuals with impaired bile production


Dosage

-Adult Dose: Typically ranges from 250 mg to 500 mg daily, divided into two or three doses, depending on the specific condition and response to treatment. -Pediatric Dose: Adjusted based on body weight and medical condition; consult a healthcare provider for specific dosing.


Contra-Indications

-Hypersensitivity to bile salts or any component of the formulation -Acute liver disease with severe impairment -Severe gallbladder disease or obstruction


Special Precautions

-Use with caution in patients with a history of liver disease. -Regular monitoring of liver function tests is recommended during treatment. -Ensure adequate hydration, especially in patients with diarrhea.


Side Effects

-Diarrhea -Abdominal cramping -Nausea or vomiting -Fatigue -Allergic reactions (rare)


Drug Interactions

-May affect the absorption of certain drugs, such as oral contraceptives and some antibiotics. -Caution when used with other medications that alter bile production or secretion.


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DISPEPTAL NICHOLAS PIRAMAL INDIA
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