Blonanserin

It is an antipsychotic agent characterized by its strong blocking action and high selectivity against dopamine-2 receptors and serotonin-2 receptors. It has stronger blocking action to dopamine-2 receptors than to serotonin-2 receptors.

Indications

Schizoprenia.

Dosage

Oral; 8-24 mg per day.

Contra-Indications

With adrenaline, azoleantifungals or HIV infected patients, CNS depressants, comatose patients, hypersensitivity.

Special Precautions

Paediatric: Data not sufficient. Pregnancy: Data not sufficient. Lactation: Data not sufficient. Elderly: Increased risk of Neuroleptic Malignant Syndrome.

Side Effects

Parkinson syndrome, akathisia, insomnia , increased blood prolactin levels, dyskinesia, somnolence, anxiety/irritability.

Drug Interactions

CYP3A4 inhibitors, levodopa.