Ceftazidime with Tazobactam
Ceftazidime with Tazobactam is a combination medication that includes Ceftazidime, a third-generation cephalosporin antibiotic, and Tazobactam, a beta-lactamase inhibitor. This combination enhances the spectrum of activity against various bacteria by inhibiting beta-lactamase enzymes, which can degrade antibiotics.-Complicated intra-abdominal infections -Complicated urinary tract infections -Hospital-acquired pneumonia -Ventilator-associated pneumonia -Skin and soft tissue infections -Gynecological infections -Septicemia
Dosage may vary based on the specific indication and patient factors. It is crucial to follow the prescribed dosage and administration instructions provided by the healthcare provider.
Ceftazidime with Tazobactam is contraindicated in individuals with a known hypersensitivity to cephalosporin antibiotics or beta-lactamase inhibitors.
-Caution in patients with a history of hypersensitivity reactions to penicillins or other beta-lactam antibiotics. -Renal impairment requires dosage adjustment. -Monitor for signs of superinfection. -Use with caution in patients with a history of gastrointestinal disease, especially colitis.
Common side effects may include nausea, diarrhea, headache, and injection site reactions. Serious side effects like allergic reactions, severe skin reactions, or changes in blood counts should be reported to a healthcare professional immediately.
-Probenecid may increase ceftazidime levels in the blood. -Concurrent use with nephrotoxic drugs may increase the risk of renal toxicity. -The concurrent use of certain anticoagulants may require dosage adjustment.
