Cefuroxime with Probenecid

Cefuroxime is a second-generation cephalosporin antibiotic that works by inhibiting bacterial cell wall synthesis. Probenecid is a uricosuric agent that increases the excretion of uric acid, primarily used to treat gout.

Indications

Cefuroxime: Respiratory tract infections, urinary tract infections, skin and soft tissue infections, otitis media, and other susceptible bacterial infections. Probenecid: Gout and hyperuricemia.

Dosage

-Dosage may vary based on the specific condition being treated. -Administer as directed by the healthcare provider. -Always complete the prescribed course.

Contra-Indications

-Hypersensitivity to cephalosporins or probenecid. -History of severe allergic reactions to penicillins.

Special Precautions

-Patients with a history of penicillin allergy should be monitored closely during cefuroxime therapy. -Probenecid should be avoided in patients with a history of hypersensitivity reactions to the drug.

Side Effects

Common side effects may include: Cefuroxime: Gastrointestinal disturbances, rash, and hypersensitivity reactions. Probenecid: Gastrointestinal upset, rash, and hypersensitivity reactions.

Drug Interactions

Cefuroxime may interact with aminoglycosides, oral anticoagulants, and probenecid. Probenecid may interact with various medications, and dosage adjustments may be necessary.