Cephradine

Cephradine is a first-generation cephalosporin antibiotic used to treat a variety of bacterial infections. It works by inhibiting the growth of bacteria and is effective against both gram-positive and some gram-negative organisms.

Indications

Cephradine is indicated for the treatment of respiratory tract infections, urinary tract infections, skin and soft tissue infections, and other bacterial infections caused by susceptible organisms.

Dosage

The dosage of cephradine varies depending on the severity of the infection and the patient's age and weight. It is typically administered orally or via injection, with dosing intervals determined by healthcare professionals.

Contra-Indications

Cephradine is contraindicated in individuals with a history of allergic reactions to cephalosporin antibiotics or penicillins.

Special Precautions

Special precautions should be taken in patients with renal impairment, as dosage adjustments may be necessary to prevent drug accumulation. It is also important to monitor for signs of allergic reactions during treatment.

Side Effects

Common side effects of cephradine may include gastrointestinal disturbances such as nausea, vomiting, and diarrhea, as well as allergic reactions such as rash and itching. Severe side effects such as anaphylaxis and pseudomembranous colitis are rare but may occur.

Drug Interactions

Cephradine may interact with other medications, including probenecid, which can increase the levels of cephradine in the body. It is important to consult with a healthcare professional before taking any other medications alongside cephradine.