Citalopram Hydrobromide
Citalopram Hydrobromide is a selective serotonin reuptake inhibitor (SSRI) used primarily for treating depression. It works by increasing the levels of serotonin, a natural substance in the brain that helps maintain mental balance.-Major depressive disorder -Anxiety disorders (off-label) -Obsessive-compulsive disorder (off-label) -Panic disorder (off-label)
-Adults: Start with 20 mg once daily, increased to 40 mg if necessary. -Elderly (?60 years): Start with 10 mg once daily, increased to 20 mg if necessary. Maximum Dose: 40 mg per day.
-Hypersensitivity to citalopram or any of its components. -Concurrent use with MAO inhibitors or pimozide. -Congenital long QT syndrome.
-Monitor for worsening depression or suicidal thoughts, especially during the initial treatment period or when the dose is adjusted. -Caution in patients with a history of seizures or mania. -Use with caution in patients with renal or hepatic impairment. -Regular ECG monitoring is recommended for patients at risk of QT prolongation.
-Common: Nausea, dry mouth, somnolence, insomnia, increased sweating, tremor. -Serious: QT prolongation, serotonin syndrome, suicidal thoughts and behaviors.
-Increased risk of serotonin syndrome with other serotonergic drugs (e.g., SSRIs, SNRIs, triptans). -Increased risk of bleeding with NSAIDs, aspirin, or anticoagulants. -QT prolongation risk with other drugs that prolong the QT interval (e.g., antipsychotics, antiarrhythmics).
