Clopidogrel with Aspirin
Clopidogrel with Aspirin is a combination medication that includes two active ingredients: clopidogrel and aspirin. Clopidogrel is an antiplatelet agent that helps prevent blood clots, while aspirin is a nonsteroidal anti-inflammatory drug (NSAID) with antiplatelet effects.This combination is prescribed to reduce the risk of heart attack, stroke, and vascular death in patients with a history of cardiovascular events or those at high risk due to various factors.
The recommended dosage may vary, and it is crucial to follow the healthcare provider's instructions. Typically, a common dosage includes a daily combination of clopidogrel (75mg) and aspirin (75-100mg).
This medication is contraindicated in individuals with hypersensitivity to clopidogrel, aspirin, or any other components of the formulation. Contraindications also include active pathological bleeding and severe liver disease.
Special precautions should be taken in patients with a history of gastrointestinal bleeding, peptic ulcers, or other bleeding disorders. Caution is advised in those with liver or kidney dysfunction. The combination should be used with care in individuals prone to asthma or allergic conditions.
Possible side effects may include bleeding, gastrointestinal discomfort, headache, and dizziness. Severe allergic reactions are rare but require immediate medical attention.
Interactions may occur with other antiplatelet agents, anticoagulants, NSAIDs, and some medications metabolized by the liver enzymes. Consultation with a healthcare professional is essential to assess potential drug interactions.