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DAPAGLIFLOZIN

DAPAGLIFLOZIN

It is a drug of the gliflozin class, that inhibit reabsorption of glucose in the kidney and therefore lower blood sugar. They act by inhibiting sodium-glucose transport protein 2 (SGLT2).

Indications

Type 2 diabetes mellitus.


Dosage

Oral; 5-10mg every morning with or without food.


Contra-Indications

Hypersensitivity, end stage renal disease, patient on dialysis.


Special Precautions

Paediatric: Safety and efficacy below 18 years not yet established. Pregnancy: Category C. Lactation: Not known if it is excreted in milk, decision to discontinue drug may be taken depending on importance of drug to mother. Elderly: In persons aged more than 75 years more side effects are seen related to kidney impairement.


Side Effects

Hypotension, Ketoacidosis, Acute Kidney Injury and Impairment in Renal Function, Urosepsis and Pyelonephritis, Hypoglycemia with Concomitant Use with Insulin and Insulin Secretagogues, Genital Mycotic Infections, Increases in Low-Density Lipoprotein Cholesterol, Bladder Cancer.


Drug Interactions

It will lead to positive urine glucose tests, urine glucose monitoring should not be done.


Other Combination Brands
Brand Name Manufactured by
Daflora-M JOHNLEE PHARMACEUTICALS PVT LTD
DAFLOZ-VD CARDIMIND PHARMACEUTICALS (A Division of Asterisk Laboratories Pvt Ltd)
DAPABERG-M HEALTHBERG BIOTECH
DAPACARD-M OLCARE LABORATORIES
DAPACROSS-MF BIOCRROSS CHEM LLP
Dapagain-M SYSTOPIC LABORATORIES LTD.
DAPALIV-M RainSun LifeCare
DAPARAS CELERA PHARMA PVT.LTD
DAPARAY M ICON LIFESCIENCES (Division of Mesmer Pharmaceuticals)
DAPARICK FREDERICK HEALTHCARE LLP
DAPARICK-MF FREDERICK HEALTHCARE LLP
Dapashield-M Gelmek Healthcare
Dapashield-M Forte Gelmek Healthcare
Dapashield-S Gelmek Healthcare
Dapashield-SM Gelmek Healthcare
Dapashield-V Gelmek Healthcare
Dapashield-VM Gelmek Healthcare
DAPILA MINITOSS MEDICINES
DAPRIZA-LG ASTER MEDIPHARMA PVT. LTD. (ASTER CARDIAC & DIABETIC)
DAPRIZA-M 10/500 ASTER MEDIPHARMA PVT. LTD. (ASTER CARDIAC & DIABETIC)
DAPRIZA-SM 10/100/500 ASTER MEDIPHARMA PVT. LTD. (ASTER CARDIAC & DIABETIC)
DAPZARA ZYRA ORGANIC
Dapzigard M LEEFORD HEALTHCARE LTD
Dapzigard M FORTE LEEFORD HEALTHCARE LTD
DAPZIGARD S LEEFORD HEALTHCARE LTD
DAPZIGARD T LEEFORD HEALTHCARE LTD
DAPZIGARD VD LEEFORD HEALTHCARE LTD
DAPZIGARD VDM LEEFORD HEALTHCARE LTD
DAPZIGARD VDM FORTE LEEFORD HEALTHCARE LTD
DYNAVIL-DP 10/100 ASTER MEDIPHARMA PVT. LTD. (ASTER CARDIAC & DIABETIC)
FREDSITA-D FREDERICK HEALTHCARE LLP
Linaprove D JOHNLEE PHARMACEUTICALS PVT LTD
Linaprove D Met JOHNLEE PHARMACEUTICALS PVT LTD
LINARICK-D FREDERICK HEALTHCARE LLP
MDP 10 SR MAGBRO HEALTHCARE PVT. LTD.
MDP 10 SR FORTE MAGBRO HEALTHCARE PVT. LTD.
MDP 5 SR MAGBRO HEALTHCARE PVT. LTD.
MDP 5 SR FORTE MAGBRO HEALTHCARE PVT. LTD.
Sitadiet-D JOHNLEE PHARMACEUTICALS PVT LTD
Sitadiet-D JOHNLEE PHARMACEUTICALS PVT LTD
Sitadiet-D JOHNLEE PHARMACEUTICALS PVT LTD
Sitadiet-D JOHNLEE PHARMACEUTICALS PVT LTD
Sitadiet-DM JOHNLEE PHARMACEUTICALS PVT LTD
SITAJAN D 50/5 HAB PHARMA
SITGLYPT D NEOCARDIABCARE DIVISION OF FINECURE PHARMA
SITGLYPT DM NEOCARDIABCARE DIVISION OF FINECURE PHARMA
SITTMENT-D CARDIMIND PHARMACEUTICALS (A Division of Asterisk Laboratories Pvt Ltd)
Tenalip-D JOHNLEE PHARMACEUTICALS PVT LTD
Vildalip-D JOHNLEE PHARMACEUTICALS PVT LTD
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