Disodium Hydrogen Citrate

Disodium Hydrogen Citrate, also known as sodium citrate dihydrate, is a sodium salt of citric acid. It is commonly used as an alkalizing agent to neutralize excess acid in the stomach and urinary tract. It is available in liquid and tablet forms for oral administration.

Indications

Disodium Hydrogen Citrate is indicated for the relief of symptoms associated with urinary tract infections and acidosis, such as burning or discomfort during urination. It can also be used to alkalize urine to enhance the excretion of certain drugs or substances from the body.

Dosage

The recommended dosage of Disodium Hydrogen Citrate varies depending on the specific indication and individual patient factors. Typically, adults may take 1 to 2 teaspoons (5 to 10 mL) of the liquid form, diluted with water, three times daily. For children, the dosage may be adjusted according to their age and weight. Always follow the healthcare provider's instructions and the prescribed dosage.

Contra-Indications

Disodium Hydrogen Citrate is contraindicated in patients with a known hypersensitivity to sodium citrate or any of its components. It should not be used in individuals with severe renal failure, hyperkalemia, or severe congestive heart failure. Caution is also advised for individuals with a history of kidney stones or a low-sodium diet.

Special Precautions

Patients with underlying medical conditions such as renal impairment or heart failure should use Disodium Hydrogen Citrate with caution and under medical supervision. Monitoring of electrolyte levels is recommended, especially for patients on other medications or with conditions affecting the kidneys.

Side Effects

Common side effects of Disodium Hydrogen Citrate may include gastrointestinal discomfort, such as nausea, vomiting, or diarrhea. Rarely, allergic reactions may occur. In high doses, metabolic alkalosis and electrolyte imbalances may develop.

Drug Interactions

Disodium Hydrogen Citrate may interact with certain medications, such as other diuretics, antacids, or medications affecting electrolyte levels. Always inform your healthcare provider of all medications, supplements, and herbal products you are taking to avoid potential interactions.