Look for Drugs and Conditions

Fexofenadine with Montelukast

Fexofenadine with Montelukast

Fexofenadine and Montelukast are medications commonly used in combination to manage allergic rhinitis and asthma. Fexofenadine is a second-generation antihistamine that reduces the effects of natural chemical histamine in the body, which can produce symptoms of sneezing, itching, watery eyes, and runny nose. Montelukast is a leukotriene receptor antagonist that helps decrease inflammation and bronchoconstriction, commonly associated with asthma and allergies.

Indications

This combination therapy is indicated for: -Seasonal allergic rhinitis (hay fever) -Perennial allergic rhinitis -Chronic idiopathic urticaria (hives) -Asthma management


Dosage

-Adults and children over 12 years: Typically, the dosage is one tablet (containing 180 mg of Fexofenadine and 10 mg of Montelukast) taken once daily in the evening. -Children aged 6-12 years: The dosage might be adjusted based on specific medical advice, often lower than the adult dose. -Children under 6 years: Use is generally not recommended without specific pediatric consultation.


Contra-Indications

-Hypersensitivity to Fexofenadine, Montelukast, or any component of the formulation. -Severe hepatic impairment (for Montelukast).


Special Precautions

-Hepatic impairment: Montelukast is metabolized in the liver, so caution is advised in patients with liver issues. -Renal impairment: Adjustments may be necessary since Fexofenadine is excreted via the kidneys. -Pregnancy and lactation: Should only be used if the potential benefits justify the potential risk to the fetus or infant. -Elderly patients: Use with caution due to possible reduced hepatic, renal, or cardiac function.


Side Effects

-Common side effects: Headache, dizziness, fatigue, dry mouth, and gastrointestinal disturbances. -Serious side effects: Mood changes, hallucinations, flu-like symptoms, and signs of liver problems (such as jaundice or dark urine). -Rare side effects: Severe allergic reactions including rash, itching/swelling, and trouble breathing.


Drug Interactions

-Ketoconazole and Erythromycin: Can increase the plasma concentration of Fexofenadine. -Phenobarbital and Rifampin: Can decrease the effectiveness of Montelukast. -Alcohol and CNS depressants: Concurrent use can enhance CNS depression. -Other antihistamines or leukotriene inhibitors: Use with caution to avoid additive effects or interactions.


Other Brands With Same Generic
Brand Name Manufactured by
AFINEDAY INDCHEMIE HEALTH SPECIALITIES PVT. LTD.
AIRSET-FX SEHAT PHARMA PVT. LTD.
ALERWIN-FM BIO CLARIS DRUGS
ALFIO-FX SANDMARTIN PHARMA
ALLOX-M RONAK LIFECARE PRIVATE LIMITED
ANRIZ-FX ENRICO PHARMACEUTICALS
ASTAZIN FX ZENOVA THERAPEUTICALS PVT. LTD. (A. Div. of Wintech Pharmaceuticals)
BAXIKAST-FX WELLSBURG
BAYUMONT FX BAYU HEALTHCARE
ENAFEX-M INCEPTA Division Of Aster Medipharm Pvt. Ltd
FEEGRA-M JOHNLEE PHARMACEUTICALS PVT LTD
FENAXOTIC-FX XOTIC MEDICARE PVT.LTD
FENOFEX M APCO PHARMA LTD.
FEUXO-M NOVIQUE LIFESCIENCES
FEXCEPT-MT MEDICONCEPT
FEXET-M LEZAA BIOTECH
FEXIA-M Kaizen Pharmaceuticals
FEXOALLIT-M ALLITO BIOCARE
FEXOBAX-M LIFEKYOR PHARMACEUTICALS
FEXOCAN-M RELIANCE LIFECARE PVT LTD
FEXODAN-M ABROS (DIVISION OF LUMAIRE LABS PVT. LTD.)
FEXOLAST PHOENIX PHARMA
FEXOLEY-M Zodley Pharmaceuticals Pvt. Ltd.
FEXOLI-MA ARCHICARE
FEXOLL-M ARCHICARE
FEXOMONT HOCHEST BIOTECH
FEXONEZ-M SITNEZ BIOCARE PVT. LTD.
FEXONIP-M Naira Derma (Div. of Dhamus Pharma)
FEXOSAP-M SAPHNIX MEDICURE
FEXOT-MF PHARM BIOTECH
FEXOZ-M Zenoks Biotech Pvt. Ltd.
FEXRIL-M TANSY MOLEQULE
FEXUR-M KAVYA HEALTHCARE
FILFAST-M ASTERISK LABORATORIES (I) PVT. LTD.
FM 24 WOCKHARDT PVT.LTD.
FODIN-M ANGEL BIOTECH
FRAGHIST Milimax Health Care Pvt. Ltd.
FXCET-M FOREX PHARMACEUTICAL
GLEMONT F GLENMARK PHARMA
HG MONTE PLUS HEALTH GUARD (INDIA) PRIVATE LIMITED
HISTOS-M WINSOME LABORATORIES LTD.
KASTOVA- FX Valunova Lifesciences Pvt Ltd (Division of Finecure Llifesciences)
LEZIL-F Sygnus Biotech
M-FEX SAIN MEDICAMENT PVT. LTD.
MONTCURE FX ALBEST MEDICARE
MONTEDINE KAPEETUS MEDICORP
MONTEN-FX BEST BIOTECH
Montey F FINECURE PHARMA
MONTFRESH F PRANSHU HEALTHCARE
MONTIFLEX MITS HEALTHCARE
MONTIZEN-FX CHIRON PHARMACEUTICALS
MONVENT FX SOLTECH LIFESCIENCES
NILCOLD FX WINTECH PHARMACEUTICALS
NIOFEX-M DERMACIA HEALTHCARE
NOVAKAST FX NOVAKIND BIO SCIENCES
OCFEX-M OCTANE BIOTECH PVT. LTD.
OSTOFEX M OSTOJ PHARMACEUTICALS
RECOFEX-M RECO DRUGS PHARMACEUTICALS LTD.
SANGRAM-M BUSAN PHARAMACEUTICALS
SERLUKAST-FX SERWIN PHARMACEUTICALS
SHAMONT FX SHARP BIOCARE
VITARESP FX ALEMBIC LTD.
Other Combination Brands
Brand Name Manufactured by
FEXOLL-MA ARCHICARE
FEXONEZ-AP SITNEZ BIOCARE PVT. LTD.
Ad 5