FUROSEMIDE

Furosemide is a potent diuretic (water pill) used to treat fluid retention (edema) in people with congestive heart failure, liver disease, or kidney disorders such as nephrotic syndrome. It works by helping the kidneys eliminate excess water and salt from the body by increasing urine production.

Indications

-Treatment of edema associated with congestive heart failure -Treatment of edema associated with renal disease (such as nephrotic syndrome) -Treatment of hypertension (high blood pressure)

Dosage

Dosage varies depending on the condition being treated and individual patient factors. Typical doses range from 20 mg to 80 mg per day orally, with higher doses possible in severe cases. Intravenous administration is also used for rapid onset in acute situations.

Contra-Indications

-Allergy to furosemide or sulfonylurea drugs -Anuria (no urine production) -Severe electrolyte imbalance (e.g., low potassium levels) -Pre-coma associated with liver cirrhosis -Pregnancy (especially during the first trimester)

Special Precautions

-Monitor electrolyte levels (especially potassium) -Use cautiously in patients with impaired renal function -Adjust dosage carefully in elderly patients -Monitor blood pressure regularly

Side Effects

-Common: Dehydration, electrolyte imbalance, hypotension, dizziness -Less common: Hearing loss, rash, pancreatitis, muscle cramps

Drug Interactions

-Increased risk of toxicity with aminoglycoside antibiotics (e.g., gentamicin) -Enhanced hypotensive effect with antihypertensive drugs -Potentiated effects with NSAIDs (nonsteroidal anti-inflammatory drugs)