Glimepiride with Metformin
Glimepiride with Metformin is a combination medication used to treat type 2 diabetes mellitus. Glimepiride belongs to a class of drugs known as sulfonylureas and helps to lower blood sugar levels by stimulating the release of insulin from the pancreas. Metformin belongs to a class of drugs known as biguanides and works by decreasing the amount of sugar your liver makes and that your stomach/intestines absorb.Treatment of type 2 diabetes mellitus when diet, exercise, and single-agent therapy do not result in adequate glycemic control.
The dosage depends on the patient's medical condition and response to treatment. It is typically started low and gradually increased to minimize side effects. Regular monitoring of blood sugar levels is advised.
Known hypersensitivity to glimepiride or metformin, diabetic ketoacidosis, severe renal impairment, severe hepatic impairment, and conditions that may predispose to lactic acidosis.
Caution is advised in patients with mild to moderate renal impairment, elderly patients, and those at risk for hypoglycemia. Regular monitoring of renal function, liver function, and blood glucose levels is recommended.
Common side effects may include hypoglycemia, gastrointestinal upset (such as nausea, vomiting, diarrhea), and weight gain. Rare but serious side effects include lactic acidosis (especially in patients with risk factors).
This medication may interact with other drugs such as certain oral diabetes medications, insulin, beta-blockers, and alcohol. Always inform your doctor about all medications and supplements you are taking.
