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Homatropine Hydrobromide

Homatropine Hydrobromide

Homatropine Hydrobromide is an anticholinergic agent used primarily for its mydriatic and cycloplegic effects in ophthalmic practices. It is derived from atropine and acts by blocking the muscarinic receptors in the eye, leading to pupil dilation and temporary paralysis of the ciliary muscle.

Indications

-Pupil dilation (mydriasis) for diagnostic procedures -Cycloplegia for refraction testing -Relief of eye pain associated with iritis and uveitis


Dosage

-Adults and children (over 3 months): Instill 1-2 drops in the affected eye(s) every 10 minutes for 1 hour before examination or as directed by the physician. -Children (under 3 months): Use under medical supervision.


Contra-Indications

-Hypersensitivity to homatropine or any component of the formulation -Narrow-angle glaucoma or predisposition to glaucoma


Special Precautions

-Use with caution in patients with known hyperthyroidism, heart disease, hypertension, or urinary tract obstruction. -Avoid driving or operating machinery after administration due to potential blurred vision and light sensitivity. -Not recommended for prolonged use due to the risk of systemic toxicity.


Side Effects

-Blurred vision -Sensitivity to light (photophobia) -Increased intraocular pressure -Dry mouth, throat, and nasal passages -Allergic reactions (rare)


Drug Interactions

-Potentiated effects with other anticholinergic drugs -Possible interactions with antidepressants, antihistamines, and antipsychotic medications


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