HUMAN SOLABLE INSULIN

Human soluble insulin, also known as regular insulin, is a short-acting insulin used to manage blood sugar levels in people with diabetes. It is identical to the insulin naturally produced by the pancreas and is used to control hyperglycemia (high blood sugar). This form of insulin is typically administered via injection and works quickly to lower blood sugar levels.

Indications

Human soluble insulin is primarily indicated for the treatment of both type 1 and type 2 diabetes to control hyperglycemia. It may also be used in other situations, such as in patients with gestational diabetes or diabetic ketoacidosis (DKA), and in some cases of insulin resistance.

Dosage

The dosage of human soluble insulin varies depending on the patient's individual needs, medical condition, blood sugar levels, and other factors. It is typically injected 15 to 30 minutes before a meal, as it begins working rapidly (within 30 minutes) and has a peak effect at about 2 to 4 hours after injection. The total duration of action is around 6 to 8 hours. Dosage should be tailored by a healthcare professional and adjusted based on regular blood sugar monitoring.

Contra-Indications

Known hypersensitivity to insulin. Hypoglycemia or low blood sugar levels. Inability or unwillingness to monitor blood sugar levels regularly.

Special Precautions

-Regular monitoring of blood sugar levels is essential to avoid hypoglycemia. -Insulin needs may vary with stress, illness, exercise, and changes in diet or weight. -Caution should be exercised when switching from one insulin type to another. -Use caution when driving or operating heavy machinery if blood sugar is not well-controlled.

Side Effects

-Hypoglycemia (low blood sugar) is the most common side effect. -Allergic reactions, such as rash, itching, or swelling, at the injection site. -Lipodystrophy (abnormal fat distribution) at injection sites with prolonged use. -Weight gain may occur with long-term use.

Drug Interactions

-Other hypoglycemic agents can increase the risk of hypoglycemia. -Certain medications like corticosteroids, oral contraceptives, and beta-blockers may interfere with insulin effectiveness. -Alcohol consumption can affect blood sugar levels, leading to hypoglycemia.