Immunoglobulins

Immunoglobulins, also known as antibodies, are specialized proteins produced by the immune system to identify and neutralize foreign objects such as bacteria, viruses, and toxins. They play a crucial role in protecting the body from infections and are used therapeutically in various medical conditions.

Indications

-Primary Immunodeficiency Disorders -Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) -Immune Thrombocytopenic Purpura (ITP) -Kawasaki Disease -Certain Autoimmune Diseases

Dosage

The dosage of immunoglobulins varies depending on the specific condition being treated, the patient’s weight, and other individual factors. It is usually administered intravenously or subcutaneously. Always follow the healthcare provider’s instructions for the correct dosage and administration.

Contra-Indications

-Known hypersensitivity to immunoglobulin products -Hyperprolinaemia (high levels of proline in the blood) -Severe renal impairment (for certain formulations) -History of thromboembolic events (specific products may be contraindicated)

Special Precautions

-Monitor for allergic reactions during and after administration -Caution in patients with a history of renal issues or thromboembolic events -Use with care in individuals with a history of liver disorders -Regular monitoring of blood parameters may be required

Side Effects

-Headache -Fever -Chills -Nausea -Vomiting -Rash -Possible allergic reactions -Renal impairment (in rare cases) -Thromboembolic events (specific products)

Drug Interactions

-May interact with live vaccines, reducing their efficacy -Potential interaction with medications affecting blood clotting -Consult with a healthcare provider for a complete list of possible interactions