Degludec

Insulin Degludec is a long-acting basal insulin analog used to control blood sugar levels in patients with diabetes mellitus. It works by providing a steady level of insulin over an extended period, helping to regulate blood glucose levels throughout the day and night.

Indications

Insulin Degludec is indicated for the treatment of diabetes mellitus in adults, adolescents, and children aged 1 year and older.

Dosage

The dosage of Insulin Degludec varies depending on factors such as the patient's age, weight, insulin sensitivity, and glycemic control goals. It is typically administered once daily, preferably at the same time each day. Dosage adjustments may be necessary based on individual response and changes in lifestyle or other medications.

Contra-Indications

Insulin Degludec is contraindicated in patients with hypersensitivity to insulin degludec or any of the excipients in the formulation.

Special Precautions

Patients should be educated on proper injection techniques and self-monitoring of blood glucose levels. Insulin Degludec should be used with caution in patients with renal or hepatic impairment, as dosage adjustments may be necessary. Hypoglycemia (low blood sugar) and hyperglycemia (high blood sugar) may occur, and patients should be advised on how to recognize and manage these conditions.

Side Effects

Common side effects of Insulin Degludec include hypoglycemia, injection site reactions (such as pain, redness, or itching), weight gain, and allergic reactions. Patients should report any persistent or severe side effects to their healthcare provider.

Drug Interactions

Insulin Degludec may interact with other medications, including oral antidiabetic drugs, beta-blockers, corticosteroids, and certain medications affecting glucose metabolism. Healthcare providers should be informed of all medications, including prescription, over-the-counter, and herbal supplements, that the patient is taking.