Metaraminol Bitartarate
Metaraminol bitartrate is a sympathomimetic amine used primarily as a vasoconstrictor to treat hypotension and shock. It works by stimulating alpha-adrenergic receptors, causing peripheral vasoconstriction and increasing blood pressure.Metaraminol bitartrate is indicated for the treatment of hypotension and shock, including septic shock, spinal anesthesia-induced hypotension, and hypotension during surgery.
The dosage of metaraminol bitartrate varies depending on the patient's age, weight, and medical condition. It is typically administered intravenously, with the dosage adjusted according to the patient's response.
Metaraminol bitartrate is contraindicated in patients with hypersensitivity to the drug, severe hypertension, ventricular tachycardia, and other conditions where increased blood pressure may be harmful.
Special precautions should be taken when administering metaraminol bitartrate to patients with cardiovascular diseases, diabetes, hyperthyroidism, or renal impairment. Close monitoring of blood pressure and heart rate is essential during treatment.
Common side effects of metaraminol bitartrate may include hypertension, tachycardia, headache, nausea, vomiting, and sweating. Serious side effects such as arrhythmias and myocardial ischemia may occur with higher doses.
Metaraminol bitartrate may interact with other sympathomimetic drugs, monoamine oxidase inhibitors (MAOIs), tricyclic antidepressants, and beta-blockers. Concurrent use with these drugs may potentiate the effects or increase the risk of adverse reactions.
