Methyl Parahydroxybenzoate

Methyl Parahydroxybenzoate, also known as methylparaben, is a preservative commonly used in pharmaceuticals, cosmetics, and food products. It belongs to the class of parabens, which are esters of para-hydroxybenzoic acid. Its primary function is to prevent microbial growth and extend the shelf life of products.

Indications

Methyl Parahydroxybenzoate is indicated for use as a preservative in various topical pharmaceutical formulations, including creams, lotions, and ointments.

Dosage

The dosage of Methyl Parahydroxybenzoate varies depending on the formulation and concentration used in specific pharmaceutical or cosmetic products. It is typically included at concentrations ranging from 0.1% to 1.0%, as regulated by health authorities.

Contra-Indications

Methyl Parahydroxybenzoate should not be used in individuals with known hypersensitivity or allergy to parabens. It is also contraindicated in products applied to broken or damaged skin due to potential irritation.

Special Precautions

-Avoid contact with eyes and mucous membranes. -Use with caution in pediatric populations and pregnant or breastfeeding women, as systemic absorption could potentially occur. -Monitor for allergic reactions, although true allergies are rare.

Side Effects

Common side effects associated with Methyl Parahydroxybenzoate include local skin irritation, itching, and redness. Severe allergic reactions are rare but possible.

Drug Interactions

There are no significant drug interactions reported with Methyl Parahydroxybenzoate when used as a preservative in topical products. However, caution should be exercised when using multiple topical medications concurrently to avoid potential additive effects.