OESTRADIOL BENZONATE

Oestradiol Benzoate is a synthetic form of the hormone estradiol, a type of estrogen. It is used in hormone replacement therapy to treat symptoms associated with menopause, such as hot flashes and vaginal dryness. Oestradiol Benzoate can also be used for other hormonal imbalances and certain cases of osteoporosis.

Indications

-Menopausal symptoms such as hot flashes, night sweats, and vaginal dryness -Prevention of postmenopausal osteoporosis -Hypoestrogenism (low levels of estrogen) -Hormone replacement therapy for certain conditions

Dosage

The dosage of Oestradiol Benzoate varies depending on the condition being treated, patient response, and other factors. It is important to follow the dosage instructions provided by the healthcare provider. The typical adult dose may range from 0.5 mg to 2 mg per day.

Contra-Indications

-History of breast cancer or other estrogen-sensitive cancers -Undiagnosed vaginal bleeding -Liver disease -Pregnancy -History of thromboembolic disorders (blood clots) -Known allergy to Oestradiol Benzoate or any of its components

Special Precautions

-Regular monitoring of blood pressure and cholesterol levels -Regular breast and pelvic exams, including Pap smears -Caution in patients with a history of depression, epilepsy, or migraine -Not recommended for use during pregnancy or breastfeeding

Side Effects

-Headaches -Breast tenderness or enlargement -Nausea -Bloating or fluid retention -Weight changes -Mood swings or depression

Drug Interactions

-May interact with certain medications, such as anticoagulants, antibiotics, and anticonvulsants -May affect the metabolism of other drugs, increasing or decreasing their effectiveness -Grapefruit juice may interact with Oestradiol Benzoate and should be avoided