Para-aminobenzoic acid

Para-aminobenzoic acid (PABA) is a compound found in the vitamin B complex. It is involved in the synthesis of folic acid and is used as a dietary supplement. PABA has been historically used in various therapeutic applications, including as a sunscreen agent and for its potential benefits in treating certain skin conditions.

Indications

-Skin Conditions: Used in the treatment of skin disorders such as vitiligo and scleroderma. -Sun Protection: Applied topically in sunscreens for its UV-filtering properties. -Folic Acid Synthesis: Supplemented to aid in the production of folic acid in the body.

Dosage

-Oral Supplement: Typical dosage ranges from 30 mg to 300 mg per day, depending on the condition being treated. -Topical Application: Used in varying concentrations depending on the formulation of the sunscreen or topical product.

Contra-Indications

Hypersensitivity: Contraindicated in individuals with a known hypersensitivity or allergy to PABA or related compounds.

Special Precautions

-Pregnancy and Lactation: Safety during pregnancy and lactation has not been well-established; consult a healthcare provider before use. -Photosensitivity: Individuals with photosensitivity or sunburn should avoid topical PABA.

Side Effects

-Allergic Reactions: May cause allergic reactions such as rash, itching, or swelling. -Gastrointestinal Issues: Oral use may lead to nausea, vomiting, or abdominal discomfort.

Drug Interactions

-Anticoagulants: May interfere with anticoagulant medications, increasing the risk of bleeding. -Other Supplements: Potential interactions with other vitamin supplements, particularly those involved in folic acid metabolism.