Phenyl Hydroxy Nitrate

Phenyl Hydroxy Nitrate is a medication used primarily for the treatment of angina pectoris and other cardiovascular conditions. It works as a nitrate vasodilator, helping to relax and widen blood vessels, which reduces the workload on the heart and improves blood flow.

Indications

-Angina pectoris -Heart failure -Hypertension (in some cases) -Other conditions requiring vasodilation

Dosage

-Adults: Typically, 10-40 mg three times daily. Adjustments may be made based on patient response and tolerance. -Children: Dosage should be determined by a healthcare provider.

Contra-Indications

-Hypersensitivity to nitrates or nitrites -Severe anemia -Hypotension -Recent use of phosphodiesterase inhibitors (e.g., sildenafil) -Patients with head trauma or cerebral hemorrhage

Special Precautions

-Monitor blood pressure regularly -Use with caution in patients with liver or kidney impairment -Caution in patients with a history of stroke or myocardial infarction -Avoid sudden discontinuation to prevent rebound effects

Side Effects

-Headache -Dizziness -Hypotension Flushing -Nausea -Rash

Drug Interactions

-Phosphodiesterase inhibitors: May cause severe hypotension (e.g., sildenafil, tadalafil) Antihypertensives: Increased risk of additive hypotensive effects -Anticoagulants: Monitor for potential increased bleeding risk -Other vasodilators: May enhance the effects and side effects of Phenyl Hydroxy Nitrate