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Phenylephrine

Phenylephrine

Phenylephrine is a medication that belongs to the class of sympathomimetic agents, specifically an alpha-1 adrenergic receptor agonist. It is commonly used to treat symptoms associated with nasal congestion, sinus congestion, and hay fever. Phenylephrine works by constricting blood vessels, leading to a reduction in swelling and congestion in the nasal passages and sinuses. This results in an improvement in breathing and a decrease in symptoms related to nasal and sinus congestion.

Indications

-Phenylephrine is primarily indicated for the temporary relief of nasal congestion due to the common cold, hay fever, or other upper respiratory allergies. -Hypotension. To maintain adequate level of blood pressure during spinal and inhalation anesthesias, PSVT.


Dosage

-S/C or IM route : 2-5mg, followed if necessary by further doses of 1-10mg. -Slow IV injection : 100-500mcg, repeated as necessary after atleast 15 minutes. -IV infusion : Initial upto 180mcg/min. reduced to 30-60mcg/min according to response. -The dosage of phenylephrine can vary based on age, medical condition, and response to treatment. It is important to follow the recommended dosage instructions provided by the healthcare professional or as indicated on the product label.


Contra-Indications

-Phenylephrine is contraindicated in individuals with a known hypersensitivity or allergy to the medication. It should also be avoided in patients with severe hypertension (high blood pressure) and certain cardiovascular conditions. -Severe hyperthyroidism.


Special Precautions

-Special precautions should be taken in individuals with pre-existing medical conditions such as cardiovascular disease, diabetes, thyroid disorders, and glaucoma. It is essential to inform healthcare providers about any existing medical conditions, allergies, or medications being taken before using phenylephrine. -Severe cornorary disease.


Side Effects

-Common side effects of phenylephrine may include increased blood pressure, headache, nausea, dizziness, and difficulty sleeping. If any severe or persistent side effects occur, it is important to seek medical attention promptly. -Blurring of near vision.


Drug Interactions

-Phenylephrine may interact with other medications, including monoamine oxidase inhibitors (MAOIs), tricyclic antidepressants, and certain antihypertensive drugs. It is crucial to inform healthcare providers about all medications being taken to avoid potential interactions. -Store protected from light.


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