POLYMYXIN B SULPHATE
Polymyxin B Sulphate is an antibiotic primarily used to treat Gram-negative bacterial infections. It works by disrupting the bacterial cell membrane, leading to cell death.-Treatment of infections caused by susceptible strains of Gram-negative bacteria -Used in severe infections such as bacteremia, meningitis, urinary tract infections, and eye infections -Often employed in combination with other antibiotics for multi-drug resistant infections
-Adults: 15,000 to 25,000 units/kg/day divided into two doses -Children: 15,000 to 25,000 units/kg/day divided into two doses -Dosage may vary based on the severity of the infection and patient condition. Always follow physician’s prescription.
-Hypersensitivity to Polymyxin B or any of its components -Patients with myasthenia gravis
-Use with caution in patients with renal impairment -Monitor renal function and neurotoxicity signs -Avoid concurrent use with other neurotoxic or nephrotoxic agents
-Nephrotoxicity (kidney damage) -Neurotoxicity (nerve damage) -Dizziness -Fever -Rash
-Aminoglycosides: Increased risk of nephrotoxicity -Neuromuscular blocking agents: Enhanced neuromuscular blockade -Other nephrotoxic drugs: Increased risk of kidney damage
| Brand Name | Manufactured by |
|---|---|
| POLY-VIN | ZARA PHARMACEUTICALS |
| POLYMYX-B | AAA PHARMACEUTICALS PVT. LTD. |
| POLYMYX-B | AAA PHARMACEUTICALS PVT. LTD. |
| POLYSHIELD-B | Unifaith Biotech (P) Limited. |
