Practolol

Practolol is a non-selective beta-adrenergic receptor antagonist, commonly known as a beta-blocker. It works by blocking the action of adrenaline and other stress hormones on the heart and blood vessels, thereby reducing heart rate and blood pressure.

Indications

Practolol is indicated for the management of hypertension (high blood pressure), angina pectoris (chest pain), and certain cardiac arrhythmias (irregular heart rhythms).

Dosage

The dosage of practolol varies depending on the condition being treated, the patient's age, and medical history. It is typically taken orally as directed by a healthcare professional. Dosage adjustments may be necessary based on individual response to treatment.

Contra-Indications

Practolol is contraindicated in patients with a history of hypersensitivity to beta-blockers or any of the ingredients in the formulation. It should not be used in individuals with certain cardiac conditions such as heart block, cardiogenic shock, or severe bradycardia (slow heart rate).

Special Precautions

Patients taking practolol should be monitored closely for changes in heart rate, blood pressure, and symptoms of worsening cardiac function. It should be used with caution in patients with asthma, bronchospastic diseases, diabetes, or peripheral vascular disease. Abrupt discontinuation of practolol may exacerbate angina or precipitate myocardial infarction, so it should be tapered off gradually under medical supervision.

Side Effects

Common side effects of practolol may include fatigue, dizziness, headache, nausea, diarrhea, and cold extremities. Less common but more serious side effects may include bradycardia, hypotension, bronchospasm, heart failure, and psychiatric disturbances. Patients experiencing any adverse effects should seek medical attention promptly.

Drug Interactions

Practolol may interact with other medications, including other beta-blockers, calcium channel blockers, antiarrhythmic drugs, and medications affecting blood glucose levels. It is important to inform the healthcare provider about all medications, supplements, and herbal products being taken to avoid potential interactions.