PROTAMINE ZINC

Protamine Zinc is an insulin formulation used primarily for the management of diabetes mellitus. It combines protamine and zinc to extend the duration of insulin action, providing a more prolonged glycemic control.

Indications

Management of diabetes mellitus in patients requiring a long-acting insulin formulation.

Dosage

-The dosage of Protamine Zinc should be individualized based on the patient’s needs and glycemic control. -Typically administered via subcutaneous injection. -Dosage adjustments may be necessary based on blood glucose levels and patient response.

Contra-Indications

-Hypersensitivity to insulin or any of the components of the formulation. -Severe hypoglycemia or episodes of hypoglycemic coma.

Special Precautions

-Monitor blood glucose levels regularly. -Adjust dosage in case of changes in weight, diet, or physical activity. -Use with caution in patients with renal or hepatic impairment. -Be aware of the risk of hypoglycemia, particularly if skipping meals or engaging in excessive physical activity.

Side Effects

-Hypoglycemia (low blood sugar) -Injection site reactions (pain, redness, swelling) -Weight gain -Allergic reactions (rare) -Edema

Drug Interactions

-May interact with other antidiabetic agents, leading to an increased risk of hypoglycemia. -Potential interactions with medications that affect blood glucose levels, such as corticosteroids, diuretics, and some antihypertensives. -Adjustments in insulin dosage may be needed when used with other drugs.