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Ramipril

Ramipril

It is a highly lipophilic, long acting ACE inhibitor.It effectively reduces both supine and standing blood pressure without significant alteration in the pulse rate.

Indications

Hypertension and cardiac failure.


Dosage

Hypertension:2.5mg/day,Max:10mg/day. Cardiac failure:1.25mg/day,increased to 2.5mg once daily, Max:10mg/day


Contra-Indications

Hypersensitivity,bilateral renal artery stenosis, pregnancy, lactation, concurrent use of K+ sparing diuretics.


Special Precautions

Pregnancy, Lactation,renal & hepatic impairment.


Side Effects

Hypotension, renal impairment, angioedema, cough, hyperkalemia.


Drug Interactions

Concomitant admn of diuretics lead to serious hypotension. With potassium-sparing diuretics dangerous hypokalaemia may result.


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