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Rauvolfia Serpentina

Rauvolfia Serpentina

Rauvolfia serpentina, also known as Indian snakeroot or Sarpagandha, is a perennial shrub native to the Indian subcontinent. It belongs to the Apocynaceae family and has been traditionally used in Ayurvedic and Unani medicine for its therapeutic properties.

Indications

-Hypertension: Rauvolfia serpentina is primarily indicated for the management of high blood pressure due to its hypotensive properties. -Insomnia: It has sedative effects and may be used to treat insomnia and sleep disorders. -Psychiatric Disorders: Traditionally used to alleviate symptoms ofcertain psychiatric disorders like anxiety and schizophrenia. -Diarrhea: In some traditional systems of medicine, it has been employed to treat diarrhea. -Fever: It may have antipyretic effects and can be used to reduce fever.


Dosage

-Hypertension: 100-300 mg of powdered root or 250-500 mg of standardized extract per day, divided into two or three doses. -Insomnia: 250-500 mg of powdered root or 500-1000 mg of standardized extract before bedtime. -Psychiatric Disorders: Dosage may vary based on individual response and severity of symptoms. Consultation with a healthcare professional is advised. -Diarrhea: Dosage may vary. It's important to consult with a healthcare provider for appropriate dosing. -Fever: Dosage may vary. Consult with a healthcare provider for guidance.


Contra-Indications

Pregnancy and Lactation: Rauvolfia serpentina is contraindicated in pregnant and breastfeeding women due to potential adverse effects on fetal and infant health. Depression: Individuals with depression should avoid its use as it may exacerbate symptoms. Hypotension: It may further lower blood pressure in individuals with hypotension. Children: Use in children should be under the supervision of a healthcare professional.


Special Precautions

-Liver Impairment: Use with caution in individuals with liver impairment as it may affect liver function. -Surgery: Discontinue use at least two weeks prior to scheduled surgery due to its potential effects on blood pressure and sedation. -Driving and Operating Machinery: May cause drowsiness; avoid activities requiring mental alertness until the effects are known. -Elderly: Use with caution in elderly individuals due to the potential for increased susceptibility to adverse effects.


Side Effects

-Hypotension -Bradycardia -Dizziness -Headache -Gastrointestinal upset


Drug Interactions

-Antihypertensive medications: May enhance the hypotensive effects when taken concomitantly. -Central Nervous System Depressants: Concurrent use may potentiate sedative effects. -Digoxin: May increase serum levels of digoxin, leading to toxicity. -Monoamine Oxidase Inhibitors (MAOIs): Potential for hypertensive crisis when used together. -Beta-blockers: May potentiate the hypotensive effects of beta-blockers.


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