RECOMBIANANT HUMAN INSULIN BIPHASIC+NPH CARTRIDGES

Recombinant human insulin biphasic + NPH cartridges contain a combination of both fast-acting and intermediate-acting insulin. This blend provides immediate glucose control upon administration and sustained blood sugar regulation over time. Typically, the fast-acting insulin is an analogue of human insulin, while the intermediate-acting insulin is NPH (neutral protamine Hagedorn) insulin.

Indications

This medication is indicated for the treatment of diabetes mellitus in patients who require insulin to control hyperglycemia. It may be used by patients with type 1 or type 2 diabetes who are not adequately controlled on other insulin or oral diabetes medications.

Dosage

The dosage of recombinant human insulin biphasic + NPH varies depending on the patient's needs, including their blood sugar levels, diet, exercise habits, and other health factors. Typically, the insulin is administered subcutaneously using a pen injector or syringe. Dosage should be personalized and closely monitored by a healthcare provider.

Contra-Indications

Recombinant human insulin biphasic + NPH is contraindicated in patients with known hypersensitivity to insulin or any of the excipients in the formulation. It is also not recommended for use in patients experiencing hypoglycemia or those in diabetic ketoacidosis without adequate resuscitation.

Special Precautions

-Hypoglycemia: This medication can lead to hypoglycemia, especially if dosages are too high or meals are delayed/missed. Close monitoring of blood glucose levels is necessary. -Insulin Absorption: Factors such as exercise, stress, or illness may affect insulin absorption and efficacy. -Insulin Requirements: Changes in insulin requirements may occur with weight gain/loss, stress, or other medications. -Injection Sites: Rotate injection sites to avoid lipodystrophy or skin thickening.

Side Effects

-Hypoglycemia (low blood sugar) -Allergic reactions at the injection site (redness, swelling, itching) -Lipodystrophy or skin changes at injection sites -Weight gain -Vision changes upon initiation of treatment

Drug Interactions

-Medications That May Increase Hypoglycemia Risk: Certain oral diabetes medications, alcohol, and beta-blockers. -Medications That May Decrease Insulin Efficacy: Corticosteroids, certain diuretics, and thyroid hormones.