Rosuvastatin with Finofibrate
Rosuvastatin is a statin medication that works by reducing levels of "bad" cholesterol (low-density lipoprotein or LDL) and triglycerides in the blood while increasing levels of "good" cholesterol (high-density lipoprotein or HDL). Fenofibrate is a fibric acid derivative that helps lower triglycerides and raise HDL cholesterol.This combination medication is typically prescribed to treat patients with mixed dyslipidemia, characterized by elevated levels of both cholesterol and triglycerides. It is used as an adjunct to diet and lifestyle changes to manage lipid levels.
Dosage may vary depending on individual patient profiles and lipid level targets. Typically, a healthcare professional will prescribe the appropriate strength and frequency of the combination medication.
This medication is contraindicated in patients with a known hypersensitivity to rosuvastatin, fenofibrate, or any other components of the formulation. It is also contraindicated in individuals with active liver disease or unexplained persistent liver enzyme elevations.
-Liver Function: Regular monitoring of liver function is recommended during treatment. -Renal Impairment: Caution is advised in patients with renal impairment, and dosage adjustments may be necessary. -Myopathy: Patients should be monitored for signs of myopathy or rhabdomyolysis, especially when used in combination with other lipid-lowering agents. -Pregnancy and Lactation: Use during pregnancy and lactation should be avoided unless the potential benefit justifies the potential risk.
Common side effects may include headache, muscle pain, nausea, and abdominal discomfort. Rare but serious side effects may include liver problems, myopathy, and an increased risk of diabetes.
Caution is advised when co-administering with certain medications, including cyclosporine, gemfibrozil, and certain antiviral medications. The risk of myopathy is increased when combined with certain drugs, and dose adjustments may be necessary.
