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ROXITHROMYCIN

ROXITHROMYCIN



Indications

Pneumonia, acute bronchitis, sinusitis, pharyngitis, tonsillitis, genital infections.


Dosage

150 mg twice daily.


Contra-Indications

Concurrent administration of ergotamine type compounds


Special Precautions

Hepatic insufficiency. Paediatrics: Reduced dose necessary. Not recommended in children below the age of 6 months. Pregnancy: Safety not clearly established. Lactation: Safety not clearly established. Elderly: No special problem.


Side Effects

Nausea, vomiting, gastralgia, diarrhoea, Rare rashes, transient rises in liver transaminase.


Drug Interactions

Displace disopyramide from protein binding sites.Increase absorption of digoxin. Prolongs half life of midazolam.serum levels of terfenadine increased.leading to ventricular arrhythmia.


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