Sodium Citrate

Sodium Citrate is a sodium salt of citric acid used in various pharmaceutical and medical applications. It acts as an alkalinizing agent, helping to balance the body's acid-base levels. It is also used as a buffering agent and an anticoagulant in blood collection tubes.

Indications

-To manage metabolic acidosis -As a buffering agent in pharmaceutical formulations -As an anticoagulant in blood collection and storage

Dosage

-For metabolic acidosis: Dosage varies based on the patient's condition and response. Typically, it is administered orally or intravenously as prescribed by a healthcare provider. -For anticoagulant use: Dosage depends on the volume of blood to be collected and the specific procedure.

Contra-Indications

-Hypersensitivity to sodium citrate or any of its components -Severe renal impairment or kidney disease -Conditions requiring a low sodium diet

Special Precautions

-Use with caution in patients with a history of renal disease or electrolyte imbalances. -Monitor electrolyte levels and acid-base balance during treatment. -Adjust dosage for patients with compromised renal function.

Side Effects

-Gastrointestinal discomfort, including nausea and vomiting -Diarrhea -Electrolyte imbalances, such as hypernatremia -Allergic reactions (rare)

Drug Interactions

-May interact with other alkalinizing agents, potentially altering acid-base balance. -Can affect the absorption of certain medications, including some antibiotics. -Caution is advised when used with other medications that impact renal function.