Sulbactam Sodium

Sulbactam Sodium is a ?-lactamase inhibitor used to enhance the efficacy of ?-lactam antibiotics. It works by inhibiting the bacterial enzymes that break down these antibiotics, thereby extending their activity against resistant bacteria.

Indications

Sulbactam Sodium is indicated for the treatment of infections caused by ?-lactamase producing bacteria, including: -Respiratory tract infections -Urinary tract infections -Skin and soft tissue infections -Intra-abdominal infections -Bone and joint infections

Dosage

The dosage of Sulbactam Sodium varies based on the type and severity of the infection, as well as the patient's age and weight. It is typically administered in combination with ?-lactam antibiotics. Standard dosing guidelines should be followed as per the specific antibiotic being used.

Contra-Indications

Known hypersensitivity to Sulbactam Sodium or any other component of the formulation History of severe allergic reactions to ?-lactam antibiotics

Special Precautions

-Use with caution in patients with a history of renal impairment -Monitor for allergic reactions and gastrointestinal disturbances -Adjust dosage in patients with hepatic or renal impairment as needed

Side Effects

Common side effects may include: -Gastrointestinal upset (nausea, vomiting, diarrhea) -Allergic reactions (rash, itching, anaphylaxis) -Hepatotoxicity -Renal dysfunction

Drug Interactions

Sulbactam Sodium may interact with other medications, including: -Other antibiotics: May have additive or synergistic effects -Anticoagulants: Increased risk of bleeding -Probenecid: May increase the levels of Sulbactam Sodium in the blood