SULPHONAMIDES AND OTHER ANTIBIOTIC PREPARATIONS
They act by inhibiting an essential metabolic reaction in the bacterial cytoplasm. Individual details have been mentioned in the chapter of chemotherapeutics / antibiotics.-Sulphonamides and other antibiotic preparations are indicated for the treatment of bacterial infections such as urinary tract infections, respiratory tract infections, skin infections, and certain sexually transmitted diseases. -Bacterial vaginitis, cervicitis, post cervical cautery and in post-operative care, trichomonal infection.
The dosage of sulphonamides and other antibiotic preparations varies depending on the specific medication, the severity of the infection, and the patient's age and weight. It is essential to follow the prescribed dosage and administration instructions provided by a healthcare professional.
Contraindications may include hypersensitivity to sulphonamides or any other components of the antibiotic preparations, severe liver or kidney disease, and certain blood disorders such as porphyria.
Special precautions should be taken in patients with a history of allergic reactions to antibiotics, as well as in pregnant or breastfeeding women. It is important to use these medications cautiously in elderly patients and those with compromised renal function.
Common side effects of sulphonamides and other antibiotic preparations may include nausea, vomiting, diarrhea, rash, allergic reactions, and photosensitivity. Serious side effects such as Stevens-Johnson syndrome and toxic epidermal necrolysis are rare but may occur.
Increases blood levels of phenytoin, tolbutamide and warfarin. Potentiates antidiabetic effect of sulphonylureas.
