Teneligliptin with Metformin

Teneligliptin with Metformin is a combination medication used to treat Type 2 Diabetes Mellitus. It consists of two active ingredients: Teneligliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, and Metformin, a biguanide.

Indications

This combination is indicated for the management of Type 2 Diabetes Mellitus in adults when diet and exercise alone do not provide adequate glycemic control.

Dosage

Dosage should be individualized based on the patient's response and tolerability. Typical starting dose: One tablet daily, with or after meals. The dosage may be adjusted as per the physician's recommendation.

Contra-Indications

-Hypersensitivity to Teneligliptin or Metformin. -Severe renal impairment or end-stage renal disease. -Acute or chronic metabolic acidosis, including diabetic ketoacidosis.

Special Precautions

-Renal function should be assessed before initiating treatment and periodically thereafter. -Discontinue if lactic acidosis or pancreatitis is suspected. -Caution in patients at risk for heart failure or with a history of angioedema.

Side Effects

Common side effects may include gastrointestinal symptoms (nausea, vomiting, diarrhea), hypoglycemia, nasopharyngitis, and headache. Rare but serious side effects include lactic acidosis and pancreatitis.

Drug Interactions

-Cationic drugs that are eliminated by renal tubular secretion may interact with Metformin. -Avoid concurrent use with other DPP-4 inhibitors or medications that increase the risk of lactic acidosis.