Triamcinolone Hexacetonide Injection

Triamcinolone hexacetonide is a synthetic corticosteroid used primarily as an anti-inflammatory agent. It is formulated as an injectable suspension for intra-articular or intralesional administration.

Indications

Triamcinolone hexacetonide injection is indicated for: -Symptomatic relief of pain and inflammation associated with rheumatoid arthritis and osteoarthritis of large joints such as the knee. -Treatment of inflammatory joint conditions, including juvenile idiopathic arthritis (JIA) and synovitis.

Dosage

-The dosage and frequency of triamcinolone hexacetonide injection depend on the specific condition being treated, the size of the joint or lesion, and the patient's response to therapy. -Typically administered as a single injection into the affected joint or lesion under sterile conditions.

Contra-Indications

-Hypersensitivity to triamcinolone hexacetonide or any components of the formulation. -Systemic fungal infections.

Special Precautions

-Use caution in patients with a history of peptic ulcer disease, hypertension, diabetes mellitus, osteoporosis, or psychiatric disorders. -Monitor for signs of infection or worsening of existing infections, as corticosteroids can mask symptoms and exacerbate latent infections. --Avoid abrupt discontinuation of therapy, as this may lead to adrenal insufficiency.

Side Effects

Common side effects may include: -Injection site reactions (pain, swelling) -Flushing of the face -Mood changes -Increased appetite -Elevated blood glucose levels

Drug Interactions

Triamcinolone hexacetonide may interact with other medications, particularly other corticosteroids, immunosuppressants, and drugs affecting hepatic metabolism (e.g., barbiturates, phenytoin).