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Trimethoprim with Sulphadiazine

Trimethoprim with Sulphadiazine


Renal, urinary and respiratory tract infection. Gonorrhoea, otitis media, skin infections. Osteomyelitis, skin infections, septicaemia. Bacterial diarrhoea.


Adults and children above 12 yrs: 1 tab twice daily 6-12 yrs: 1/2 tab twice daily.


Hypersensitivity to Sulph- onamides. Pregnancy, lactation, jaundice, blood dyscrasias, renal impairment, neonates.

Special Precautions

Not recommended if creatinine clearance less than 15 ml/min and in elderly patients. Test blood regularly in long term therapy high fluid intake should be maintained. Folate deficiency.

Side Effects

Crystalluria, allergic reactions, nausea, vomiting, diarrhoea.

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