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Amlodipine

Amlodipine

It is a dihydropyridine Ca antagonist, with a long duration of action used for the treatment of hypertension and angina pectoris. It inhibits the transmembrane influx of calcium ions into the cardiac muscle and smooth muscle

Indications

Hypertension, angina including chronic stable and vasospastic types.


Dosage

5-10 mg once a day


Contra-Indications

Hypersensitivity


Special Precautions

Liver disease. Paediatrics: Not recommended. Pregnancy: Unsafe. Lactation:Unsafe.To be used if clearly indicated. Elderly: Reduce dose may be necessary.


Side Effects

Headache, fatigue, somnolence, dizziness, flushing, palpitations, nausea, peripheral oedema & abdominal pain


Drug Interactions

Potentiates effects of thiazide diuretics & ACE inhibitors.


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