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Ceftriaxone

Ceftriaxone

Ceftriaxone treats several kinds of bacterial infections. This medication is a cephalosporin antibiotic.

Indications

Meningitis, Septicaemia, Typhoid, UTI, Proplylaxis in surgical infections.


Dosage

Meningitis: Adults: 4 gm i.v. initially followed by 2 gm i.v. once daily for 10 days or 72 hours after fever abates. Children: 75-100 mg/kg body wt for 7-9 days. Typhoid : Adults: 4 gm daily for 2 days followed by 2 gm daily for 2 days. Children: 75 mg/kg body wt daily for 7 days. Other conditions : Adults: 1-2 gms daily. Children: 50-75 mg/kg body wt daily. Other conditions : Adults: 1-2 gms daily.


Contra-Indications

Hypersensitivity.


Special Precautions

Hepatic or renal dysfunction, Neonates. Paediatrics: Avoid in premature neonates. Pregnancy & Lactation: Use with caution. Elderly: Decrease dose in case of renal impairment.


Side Effects

Diarrhoea, hypo-prothrombinaemia, pseudomembranous colitis.


Drug Interactions

Disulfiram like reaction with alcohol.


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