Hydroguinine

Hydroguinine is an anti-malarial medication primarily used in the treatment and prevention of malaria. It works by inhibiting the growth of malaria parasites in the bloodstream.

Indications

-Treatment of acute malaria -Prophylaxis against malaria in endemic areas

Dosage

-Adults: Typically, 400 mg of Hydroguinine daily for 3 days, with dosage adjustments based on severity and patient response. -Children: Dosage is based on weight and should be determined by a healthcare provider.

Contra-Indications

-Known hypersensitivity to Hydroguinine or any component of the formulation Severe liver or kidney impairment -Pregnancy, especially during the first trimester, unless specifically advised by a healthcare provider

Special Precautions

-Monitor liver and kidney function regularly during treatment -Use with caution in patients with a history of cardiovascular issues -Assess for potential G6PD deficiency before starting treatment

Side Effects

-Common: Nausea, vomiting, headache, dizziness -Less common: Visual disturbances, hearing loss, allergic reactions -Rare: Severe skin reactions, blood disorders

Drug Interactions

-May interact with other anti-malarial drugs and medications that affect liver enzymes -Caution when used with drugs that affect cardiac rhythm