PIPERINE

Piperine is an alkaloid found in black pepper (Piper nigrum) and long pepper (Piper longum). It is commonly used to enhance the bioavailability of various drugs and nutrients, improving their absorption in the digestive tract.

Indications

-Enhances the bioavailability of various drugs and nutrients -Used as a supplement to improve the effectiveness of other medications

Dosage

Typical dosage ranges from 5 to 10 mg per day, often included in supplement formulations. Dosage may vary based on specific formulations and therapeutic needs.

Contra-Indications

-Piperine should be avoided by individuals with known hypersensitivity to it or to black pepper. -Caution is advised for those with gastrointestinal issues or on medication that affects liver enzymes.

Special Precautions

-Use with caution in individuals with liver disease or those taking medications metabolized by the liver. -Pregnant or breastfeeding women should consult a healthcare provider before use.

Side Effects

-Gastrointestinal discomfort -Nausea -Allergic reactions in rare cases

Drug Interactions

Piperine may interact with various medications by affecting their metabolism, including: -Anticoagulants -Antiepileptics -Certain antihypertensives -Medications metabolized by cytochrome P450 enzymes