Look for Drugs and Conditions

NIMESULIDE

NIMESULIDE

Nimesulide is a nonsteroidal anti-inflammatory drug (NSAID) that exhibits anti-inflammatory, analgesic, and antipyretic properties. It belongs to the class of selective COX-2 inhibitors. It is a analgesic and antipyretic in action,apart from its anti inflammatory action. Unlike other NSAID'S, the chemical structure of nimesulide does not contain a carboxylic group but a sulfonanilide moiety as the acidic group. It is absorbed rapidly and completely after oral administration. It acts by inhibiting the release of tumour necrosis factor-alpha, acts as a competitive inhibitor of histamine release and reduces superoxide anion formation.

Indications

-Nimesulide is commonly prescribed for the treatment of acute pain, inflammation, and fever associated with various conditions such as musculoskeletal disorders, dental pain, and dysmenorrhea. -Rheumatoid arthritis, osteoarthritis, other degenerative joint disorders, musculoskeletal disorders, low back pain, dysmenorrhoea, gynaecological conditions, thrombophlebitis dental pain and in ENT inflammations. In children:Fever&other sign and in RT Inflammation.


Dosage

-The dosage of nimesulide varies depending on the specific condition being treated. It is typically administered orally, and the recommended dose should be followed as per the prescribing healthcare professional's instructions. -Adults: 100 mg twice daily, -Children:: 5mg/kg/day in 2 or 3 divided doses.


Contra-Indications

-Nimesulide is contraindicated in individuals with a history of hypersensitivity or allergic reactions to NSAIDs. It should be avoided in patients with severe hepatic impairment, gastrointestinal bleeding, or active peptic ulcer. -Hypersensitivity, active peptic ulcer disease, hepatic impairment.


Special Precautions

-Special precautions should be taken in patients with a history of cardiovascular diseases, renal impairment, and those who are elderly. It is advised to monitor liver function regularly during treatment. Avoid concurrent use with other NSAIDs, and caution is needed in patients with a history of gastrointestinal disorders. -Active peptic ulcer, elderly patients with moderate renal impairment, congestive heart failure or cirrhosis. Paediatrics: Reduced dose is necessary. Pregnancy: Contraindicated. Lactation: Use with caution. Elderly: Use only, if clearly indicated.


Side Effects

-Common side effects of nimesulide include gastrointestinal disturbances such as nausea, dyspepsia, and abdominal pain. Serious adverse effects may include hepatotoxicity, skin reactions, and cardiovascular events. If any unusual symptoms occur, medical attention should be sought promptly. -Epigastric pain, heart burn, nausea, diarrhoea, vomiting, skin rash, pruritus, dizziness, somnolescence, headache.


Drug Interactions

-Nimesulide may interact with certain medications, including anticoagulants, antiplatelet drugs, diuretics, and other NSAIDs. It is important to inform healthcare providers about all medications being taken to avoid potential interactions. -Displace methotrexate from its binding sites, decrease the plasma level of theophylline, oral bioavailability of frusemide may be reduced, displaced by the concomitant use of fenofibrate, salicylic acid, valproic acid.


Other Brands With Same Generic
Brand Name Manufactured by
AFFYNIM-100 AFFY PHARMA
AMONIM-MD MAK PHARMA
ARNOLD- DT QUEST PHARMACEUTICALS
ARTHOGESIC DR JOHNS LAB HEALTHCARE
ASKALIDE ASKLEPIOS REMEDIES
B-LID-DT BLAZON BIOTEK
BENICE-DT Bionet India Pvt. Ltd.
BENICE-DT Bionet India Pvt. Ltd.
BLISULIDE BLISS GVS
BULIDE-100 BIOCARE REMEDIES PRIVATE LIMITED
CARNIM MEDIAID LAB
CASLIDE CASCA REMEDIES
CHIMOL-N Euporie Pharmaceuticals
CRUSID-MD EVENTS PHARMACEUTICALS PVT. LTD.
DARDNIL hiral Labs
DICRIL GENASIA HEALTHCARE
DIPLONIM PHARMATECH HEALTHCARE
DISNIM STEDCHEM OF INDIA
EZEE-PAIN DT FAIR DEAL LIFE CARE
FLEXULID WONDER HEALTHCARE
GAT-MD THRIFT PHARMACEUTICALS PVT. LTD.
IMOSAN-100 MD ARVINCARE
JUMSULID FOREX PHARMACEUTICAL
KAZOLID-MD Kaizen Drugs
MAXIFLAM KAPL
MELIDE MD MILIMAX HEALTHCARE
MESULID STADMED PRIVATE LIMITED
MEXO DAVIDSON PHARMACEUTICALS
MISE DR. NISE PVT. LTD.
N-SIDE CFL PHARMACEUTICALS LTD.
NAM LINCOLN PHARMACEUTICALS LTD.
NAPSLIDE DR. AP HEALTHCARE
NEGESIC NPS PHARMACEUTICALS
NEME MD WEL N DRUGS
NEMERIV EAST AFRICAN REMEDIES
NEMU RHOMBUS PHARMA PRIVATE LIMITED
NEST SCHWITZ BIOTECH
NICIP CIPLA
NIDE (BLUE,SILVER,YELLOW) Universal Health Sciences
NILD ALKA PHARMACEUTICALS
NILE NORDIC PHARMACEUTICALS LTD
NILIDE CADILA PHARMACEUTICALS LTD.
NILIDE GEL CADILA PHARMACEUTICALS LTD.
NIM WEISHORN BIOTECH
NIM-LOOSE WEISHORN BIOTECH
NIMACE MD WINTECH PHARMACEUTICALS
NIMCARE ALDE MEDI IMPEX
NIMDEX OCTANE BIOTECH PVT. LTD.
NIMDUS CADILA PHARMACEUTICALS LTD.
NIME-MD ARCHISE LIFE SCIENCE
NIMEB TAURUS LABORATORIES PVT. LTD.
NIMEB-MD TAURUS LABORATORIES PVT. LTD.
NIMEGESIC ALEMBIC LTD.
NIMEGESIC TRANSGEL ALEMBIC LTD.
NIMEGESIC-I.R. ALEMBIC LTD.
NIMERIL ALBERT DAVID LTD.
NIMERON RONAK LIFECARE PRIVATE LIMITED
NIMEX Lanark Laboratories
NIMFAST ZYDUS VACCICARE
NIMFAST CADILA PHARMACEUTICALS LTD.
NIMFLA PROCTOR ORGANICS
NIMICA GEL IPCA LABS LTD.
NIMILID MD ZENOVA THERAPEUTICALS PVT. LTD.
NIMIND INDOCO REMEDIES LTD.
NIMIND CT INDOCO REMEDIES LTD.
NIMIRAD RADDISON HEALTH CARE PVT. LTD.
NIMISE-MD KAPEETUS MEDICORP
NIMJET TRIO REMEDIES PVT. LTD.
NIMKAIR PDC HEALTHCARE
Nimkul FINECURE PHARMA
NIMLEY-MD Zodley Pharmaceuticals Pvt. Ltd.
NIMLODI AJANTA PHARMA LTD.
NIMLOO MANTECH PHARMACIA PVT.LTD.
NIMOCROS -AMBER BIOCRROSS CHEM LLP
NIMORAN NRD HEALTHCARE
NIMOROSS GREEN BIOCRROSS CHEM LLP
NIMOTAS-CD INTAS PHARMACEUTICALS LTD.
NIMOTIL GNOSIS PHARMACEUTICALS PVT. LTD.
NIMP RB REMEDIES
NIMPACT-MD DR. ETHIX's
NIMRIT FORRIT LIFECARE
NIMROX WONDER ASROX
NIMSAID MEDLEY
NIMSULA HAMAX PHARMACEUTICALS
NIMTO SILICON PHARMA
NIMUCARE MEDICO HEALTHCARE
NIMUDE-MD MERRIL PHARMA PVT. LTD
NIMUDER WONDER HEALTHCARE
NIMULID PANACEA BIOTEC LTD.
NIMULID TRANSGEL PANACEA BIOTEC LTD.
NIMULID-EF PANACEA BIOTEC LTD.
NIMULID-MD PANACEA BIOTEC LTD.
NIMURICK-100 FREDERICK HEALTHCARE LLP
NIMUSPA INDOCO REMEDIES LTD.
NIMVON MD AJANTA PHARMA LTD.
NIN-100 HAIGEN MEDILINE
NINSIT SITNEZ BIOCARE PVT. LTD.
NISE Dr Reddy's Laboratories Ltd
NISLID-MD ZORION DRUGS & HERBS PVT.LTD
NIXIA WANDER
NIZER USV LTD.
NOVOGESIC GLENMARK PHARMA
NSR MD TAB STANDARD REMEDIES PVT. LTD.
NUSE CAPITAL PHARMA
NYME Prism Pharma
NYME-100 Prism Pharma
NYMZAP SYMBIOSIS LIFESCIENCES
OPUL MISSION HAPPINESS DIVINE PVT LTD
ORNIM DYNAMIC LABORATORIES PVT. LTD.
ORTHOBID NICHOLAS PIRAMAL INDIA
ORTHOBID NICHOLAS PIRAMAL INDIA
REDFAST MARC LABORATORIES PVT. LTD
REDNIM-MD MARTYN NIKK PHARMA PRIVATE LIMITED
REDYNISE Dr Reddy's Laboratories Ltd
RHYNIM RHYTHM MEDICARE
RYTE WYN BURG PHARMACEUTICALS
SOFTEL-MD Symbiosis Lab
SOONIL WALLACE PHARMACEUTICALS LTD
SYMOLID SYMBIOSIS PHARMACEUTICALS PVT. LTD.
ULIDE-M APCO PHARMA LTD.
VIKNIM ANVIK BIOTECH
VISTANIM Minova lifesciences PVT.LTD.
WINAID WINSON LABORATORIES
ZEGA Sun Pharmaceutical Industries Ltd.
ZELID ZEE LABORATORIES
ZELIDE SUNRISE REMEDIES PVT. LTD
ZEN ZICAD LIFE CARE
ZOLANDIN NICHOLAS PIRAMAL INDIA
ZOLANDIN NICHOLAS PIRAMAL INDIA
Other Combination Brands
Brand Name Manufactured by
4NT-COLD Bionet India Pvt. Ltd.
Achnim - P Regency Healthcare
ACTISYN ZENOVA THERAPEUTICALS PVT. LTD.
ALSOLIDE-M.R DR. ALSON LABORATORIES LTD.
ANAFEBRIN THEMIS CHEMICALS
ANGINAC-COLD ENRICO PHARMACEUTICALS
ARNOLD-P QUEST PHARMACEUTICALS
ASKALIDE-MR ASKLEPIOS REMEDIES
CANAM-COLD CANSAS LIFECARE
CETCOLD PLUS RONAK LIFECARE PRIVATE LIMITED
CYCLOZOBID NICHOLAS PIRAMAL INDIA
DROLIDE RADIX
ECONIM P AMWIN PHARMA PVT LTD
LIGESIC N+ LIZA LIFE SCIENCE
LOTHERMA-N NOVAKIND BIO SCIENCES
LUMFLAM PHONEX PHARMA (DIVISION OF LUMAIRE LABS PVT. LTD.)
ME PLUS PALAS PHARMA
MICRONIM-P MICRO ORGANICS PHARMACEUTICALS (INDIA) PVT. LTD.
MOLID ZYGAL PHARMACEUTICALS PVT. LTD
N P GOLD GLORIOUS MEDICARE
N-CETA AAN PHARMA PVT LTD
NAM PLUS LINCOLN PHARMACEUTICALS LTD.
NAP SPAS RADDISON HEALTH CARE PVT. LTD.
NELSIM COLD & FLU MARXX PHARMA
NEMERIV-D EAST AFRICAN REMEDIES
NEWCET TOTAL COLD LEO FORMULATIONS (P) LTD.
NICEPTA-P INCEPTA Division Of Aster Medipharm Pvt. Ltd
NILCOLD + WINTECH PHARMACEUTICALS
NIMBRA PLUS D/L INDKUS BIOTECH INDIA
NIMESUMOL-COLD CULMEN
NIMIP MEDLIFE GENETICS
Nimkul para FINECURE PHARMA
NIMUCIP COLD & EXTRA MARXX PHARMA
NIMUCIP COLD & FLU MARXX PHARMA
NIMUFLEX-MR NICHOLAS PIRAMAL INDIA
NIMULID NUGEL PANACEA BIOTEC LTD.
NIMUPRINA-P PRINA HEALTHCARE
NIMUZEN P AMWIN PHARMA PVT LTD
NISPA INVOMED COTAB PVT. LTD.
NISPA INJECTO CAPTA PVT. LTD.
NISS INJECTO CAPTA PVT. LTD.
NIWAY-PLUS ASTER MEDIPHARMA PVT. LTD.
NIZER USV LTD.
NPL AAN PHARMA PVT LTD
P-NYME Prism Pharma
Painrelax N ALOBIOTE DIVISION OF FINECURE PHARMA
PARASIDE GRANT MEDICAL COLLEGE AND SIR JJ GROUP OF HOSPITAL
REDNIM-P MARTYN NIKK PHARMA PRIVATE LIMITED
REMICOLD-P REMANDISH PHARMA PVT LTD
RITZ P ACTIVE STANDARD REMEDIES PVT. LTD.
RITZ-P DS TAB STANDARD REMEDIES PVT. LTD.
ROBILID KHANDELWAL LABORATORIES (P) LTD.
SPASMONICE MERIND LIMITED
SYRMAC GM REMANDISH PHARMA PVT LTD
TIDE-P PHARMA DRUGS AND CHEMICALS
ULIDE PLUS APCO PHARMA LTD.
ZIYACOLD AROMA LIFE SCIENCE
ZOLANDIN MR NICHOLAS PIRAMAL INDIA
Ad 5